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Neurons, astrocytes, and oligodendrocytes all express it, and IGF-1 signaling has documented roles in neurogenesis, synaptogenesis, myelination, and neuronal survival
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Endocrinology 150 , 707712 (2009)
Most resolve within a few days without treatment
Causes range from relatively minor ones that can be treated at home (like hemorrhoids), to serious emergencies (like colorectal cancer)
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